(Adnkronos) - “Strategia d’intervento deve essere mirata precoce e personalizzata e questo può rivoluzionare la gestione della patologia consentendo risultati che sembravano irragiungibili”.
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00:00Dermatitis is an atopic dermatitis, a chronic inflammatory disease of the skin in the pediatric stage, with a prevalence of about 20%, although recent data have shown that about 10% of teenagers and adults suffer from it.
00:17For its most typical symptoms, such as continuous itching and the presence of visible spots on the skin, it can also have significant repercussions on the quality of life of those who suffer from it.
00:27For this reason, Ersilia Tolino, Director of the Complex Operating Unit of Dermatology and Responsible for Atopic Dermatitis in Chronic Inflammatory Diseases and Cutaneous Diseases of the Fiorini Hospital in Terracina, in the province of Latina, should be diagnosed early and then treated in an admired and personalized way.
00:47Atopic dermatitis is a diagnostic challenge, both for the clinical heterogeneity of the disease and for the diagnostic complexity. In fact, we remember that a wide variety of cutaneous diseases share signs and symptoms of atopic dermatitis, but also for the inadequate response to traditional therapies.
01:03But how is this pathology diagnosed in practice?
01:07The diagnosis is based on anamnesis and clinical examination, on the familiarity with atopic diseases, on the pruritus and on the presence of typical lesions, which are rheumatoid clots that can evolve towards plaque, rheumatoid, papulovascular, which are symptoms of scarring and scarring lesions, with a tendency to bacterial overinfection.
01:27Thanks, however, to the progress of research in this field, significant steps have been taken today, in particular with a new class of drugs.
01:36In the therapeutic scenario, as for the most recent introduction of biological drugs, there are inhibitors, which are small molecules that block the enzyme Januskinase, intervening both on inflammation and pruritus.
01:49These drugs have the advantage of oral supply, of rapidity, both in terms of effectiveness and on the pruritus symptom, which we know to be fundamental in atopic dermatitis, a sleep-disturbing dermatitis with an important impact on social life and on work productivity.
02:05Our experience is that the intervention strategy on atopic dermatitis must be targeted and precocious.
02:10The path of care must be much more personalized on the characteristics of the patient, with temporary access to therapies.
02:18In fact, this can revolutionize the management of atopic dermatitis, allowing results that until recently seemed unattainable.