Wanda emerges from a traumatic divorce. She temporarily lives with her sister Gloria and brother-in-law Lucas. To help her recover from depression, Gloria and Lucas suggest that Wanda undergo an experimental sleep study, run by Dr. Richard Pretorious. In addition to her, Margo, Porter, and Theo participate in the experiment. After the first tests, the subjects of the experiment begin to have strange visions and all of them, during their sleep, begin to dream of a monstrous creature.
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