• 2 months ago
Basedow's disease has many synonyms: Graves' disease, diffuse toxic goiter, Flajani disease, Perry's disease, hyperthyroidism.
The main characteristic of Graves' disease is an increase in the activity and volume of the thyroid gland due to iodine deficiency in the body.
Hyperthyroidism is the second most common thyroid disease, which can be transmitted by heredity through the female line: from grandmother to granddaughter.
The occurrence of Graves' disease is associated with the appearance of defects in the functioning of the immune system, due to which an abnormal form of protein is produced, which harms the thyroid gland.
According to statistics, out of 100 people, 1 suffers from Graves' disease, but most often these are young women.
Causes of Basedow's disease may include: long-term chronic infections in the body, hereditary predisposition, viral infections, radioactive iodine, chronic tonsillitis, diabetes, Addison's disease, vitiligo, hypoparathyroidism.
Common signs of diffuse toxic goiter are: vomiting, nausea, enlarged thyroid gland.
At the early stage of hyperthyroidism, the following symptoms may be observed: sleep disturbances, trembling fingers, palpitations, increased sweating, mood swings, poor heat tolerance, weight loss.
Characteristic of Graves' disease are changes at the eye level: exophthalmos, a feeling of sand in the eyes, a pronounced shine in the eyes.
Dangerous changes are observed at the level of the cardiovascular system: heart rhythm disturbances, increased blood pressure, rapid heartbeat, angina.
Disturbances are also observed at the level of the nervous system, liver and digestive tract. Also, diffuse toxic goiter may be characterized by infertility and impotence.
Basedow's disease has 3 stages: mild, moderate and severe.
Diagnosis of diffuse toxic goiter is made on the basis of: clinical picture, ultrasound examination, palpation of the thyroid gland, analysis of the concentration of thyroid hormones in the blood.
Treatment of Graves' disease includes taking medications (antithyroid drugs): propicil, thiamazole, carbimizole.
If treatment is ineffective, surgery or treatment with radioactive iodine is used.
Prevention of diffuse toxic goiter includes: lifestyle control, health monitoring, timely treatment of chronic and viral infections, elimination of stress and anxiety.
Attention! This material is for informational purposes only. Before using any methods and means of treatment, it is recommended to consult a doctor!
Transcript
00:00Basiedov-Greyev's disease causes symptoms, treatment and prevention, interesting about
00:06science and medicine, prepared by the editors of the channel AllScientifical.
00:10Basiedov's disease or Greyev's disease, the first toxic goiter, Flayani's disease,
00:22Perry's disease, is a disease characterized by increased activity of the thyroid gland
00:27and increasing the size of this gland due to autoimmune processes in the body.
00:37With goiter, an increase in the thyroid gland is observed due to rapid proliferation of
00:43cells in this gland, as a rule, this disease is associated with a lack of iodine in the
00:48body.
01:00Hyperthyroidism is one of the most common thyroid diseases, a few cases of this disease
01:07are less common than hyperthyroidism, it is still the second place after it among thyroid
01:14diseases.
01:20Basiedov's disease in many cases is inherited through the female line, most often the disease
01:27is transmitted through a generation from grandmother to granddaughter.
01:37As mentioned above, Greyev's disease is an autoimmune disease, it is the result of
01:44defects in the immune system, which begin to produce substances that interfere with
01:49the normal function of the body.
01:51The first goiter is characterized by the fact that lymphocytes begin to produce an abnormal
01:57form of protein that has a stimulating effect on the thyroid gland, this protein is called
02:03long-acting thyroid stimulator.
02:11Diffuse goiter, toxic goiter, is a very common disease, one patient per 100 people, most
02:17often young and middle-aged women suffer from it.
02:31The causes of Greyev's disease can be different, long-term chronic infection in the body, hereditary
02:39predisposition, viral infection, radioactive iodine, chronic tonsillitis, diabetes, idison
02:47disease with illegal hypoparathyroidism.
02:54General signs of diffuse toxic goiter, symptoms of Greyev's disease are almost the same
02:59as with hypothyroidism, which in many cases is the initial form of a disease.
03:05The disorder is characterized by symptoms such as vomiting, nausea, enlargement of the
03:10thyroid gland.
03:22Yearly symptoms of Basildov's disease, in the early stage of the disease visible symptoms
03:27are almost not noticeable.
03:29Greyev's disease, Basildov's disease, in many cases has individual symptoms, which
03:34makes it difficult to determine the correct diagnosis.
03:39Among the first symptoms you can notice sleep disturbance, trembling fingers, hair palpitation,
03:44crazy sweating, mood swings.
03:47More common symptoms include poor head tolerance, weight loss, even with normal nutrition.
04:05Change at eye level in Greyev's disease.
04:07A specific symptom of Greyev's disease is considered to be modification in the eye area,
04:13pronounced shine of the eyes, rare blinking, dark limbal symptoms, wide open eyes.
04:19Other things may also appear, such as eye damage, enlargement and bulging of the eye,
04:25aches of the thalamus, sensation of the sun in the eyes, double vision, which looking
04:31down with open eyes, a white stripe appears above the pupil.
04:36In healthy patients this does not happen because the eyelids, as usual, follow the eyeball.
04:43In patients, an increase in bulging of the eyeball is observed, sometimes the eyelids
04:48are characterized by swelling.
04:50Impaired nutrition of the eyes can cause various eye infections, inflammation of the mucous
04:56membrane of the eye, conjunctivitis, where nutrition of the eyeball is disturbed, optic
05:02neuritis appears.
05:03As a result, the patient may become blind.
05:07Skin modification, Basildov's disease.
05:09As the disease evolves, the patient's tremors become more noticeable through the body, the
05:15skin becomes moist, the patients are fuzzy, the skin through the body takes a dark shade
05:21and is more pronounced in the eyelid area, in some cases the skin in the area of the
05:26shines and feet thickens, the form of a dense edema, the volume of the thyroid gland increases
05:32and becomes more noticeable, when palpated, it has a dense character and no pain is felt.
05:40Cardiovascular disorders in goiters.
05:44Some of the most severe manifestations of diffuse toxic goiters are considered to be
05:49cardiovascular disorders.
05:51The patient begins to experience problems such as heart rate disturbances, rapid heartbeat,
05:57even during sleep.
05:59Many elderly patients often experience attacks of angina, an increase in blood pressure is
06:05noted.
06:06This disease can cause fatal heart failure.
06:12Increased motility of the gastrointestinal tract.
06:16Increased thyroid activity increases the motility of the gastrointestinal tract.
06:21The following symptoms appear.
06:23Nausea, diarrhea, and vomiting less often.
06:31Liver problems with goiter.
06:33With an excess of thyroid hormones, the liver can suffer because they have a toxic effect
06:38on this organ.
06:40In some cases, fatty liver degeneration develops.
06:49Disruption of the nervous system in basidov's disease.
06:52A high concentration of thyroid hormones in the blood can affect the functions of the
06:58central nervous system.
07:00Such conditions as insomnia, dizziness, headache, anxiety.
07:09Impotence and infertility in Graves' disease.
07:11With hyperactivity of thyroid glands, there are also disorders of the functions of other
07:17endocrine organs, and even genitals.
07:20A man's potency decreases.
07:22For a woman, the situation can become more complicated because menstrual irregularities
07:28and even infertility are observed.
07:32Distortion of sugar metabolism basidov's disease.
07:35There is an increase in the production of hormones by the adrenal cortex and glucose
07:41metabolites disorders, because of the latter, the patient is at risk of developing diabetes.
07:52Stage of Graves' disease.
07:54There are three stages of Graves' disease, mild, moderate, severe.
07:57First stage.
07:58During the first stage, the patient feels well.
08:00The purity of the heart contraction does not exceed 100 beats per minute.
08:05The patient notices a 10% weight loss.
08:08Moderate stage.
08:09During the moderate stage of the disorder, the pulse rises about 100 beats per minute.
08:14Blood pressure also increases and weight decreases by 20%.
08:20Severe stage.
08:21The severe stage is characterized by a weight loss of more than 20% and pulse rises above
08:27120 beats per minute, and side effects of the disease on other organs are observed.
08:45Diagnosis of basidov's disease.
08:47Diagnosis of Graves' disease is based on clinical picture, ultrasound examination,
08:52palpation of the thyroid gland, analysis of the concentration of thyroid hormones in the
08:57blood.
09:02Treatment of Graves' disease.
09:04Drug treatment.
09:05Treatment of Graves' disease is carried out by drug method.
09:07The main prescribed drugs that suppress the activity of the thyroid gland are thyrostatics
09:13propichil carbamazole, thiamazole.
09:16At the beginning of the disease, high doses of drugs are used, which are reduced over
09:21time.
09:22Treatment of the disease is carried out by monitoring the level of thyroid hormones in
09:26the blood until all signs of the Graves' disease disappear, at least a year.
09:31Also used are beta blockers, glucocorticoids, immunocorrectors, levothyroxine.
09:44Surgical intervention for diffuse toxic gutter.
09:47If drug treatment does not help, the surgical treatment is performed, in which way part
09:53of the thyroid gland is removed.
09:55Removing part of the thyroid gland does not eliminate the cause of the disorder.
10:00Radioactive iodine treatment.
10:03Another method of treating Graves' disease if medications are ineffective is treatment
10:08with radioactive iodine.
10:10This method is inacceptable for young people of childbearing age, but is great for older
10:15people.
10:16Radioactive iodine entering the body damages the cells of the thyroid gland and, as a result,
10:21the activity of the gland decreases.
10:23During treatment of the disease, it is necessary to reduce the amount of products rich in iodine
10:28and not to take iodized salt.
10:30Some bathing during treatment is also not recommended because there is a risk of making
10:35the treatment ineffective.
10:40Prevention of toxic diffuse gutter.
10:43Prevention of disease consists of the following measures.
10:47Lifestyle control.
10:48Health control.
10:49Timely treatment of chronic and viral infections.
10:51Very many cases can cause Graves' disease.
10:54You can be nervous and sound.
10:56Stress can only do harm.
10:59Graves' disease most often manifests itself at the age 30-40 years, which is why it is
11:05recommended to visit an endocrinologist more often at this age.

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