Pfizer’s COVID-19 Vaccine May Be Less Effective in Obese People, Study Says

  • 3 years ago
Pfizer’s COVID-19 Vaccine
May Be Less Effective in
Obese People, Study Says.
Researchers in Italy
have discovered that the
Pfizer/BioNTech vaccine
may be less effective in
obese individuals. .
Their study, which has not been peer reviewed,
followed the antibody response caused by two
doses of the Pfizer/BioNTech vaccine.
In 248 healthcare workers, 99.5 percent were
found to have developed an antibody response. .
In people who were overweight and
obese, that response was found to be blunted.
In a separate study of healthcare workers in
Brazil, COVID-19 reinfection was more common
among people with a higher BMI.
Excess body fat can cause metabolic changes
such as inflammation and insulin resistance.
This constant state of low-grade inflammation
can weaken immune responses, which means
it’s harder for the body to fight off infection. .
Previous research has found
that obesity, aka a BMI over
30, increases the risk of
dying from COVID-19
by almost 50 percent. .
It also increases
the risk of being
hospitalized with
COVID-19 by
113 percent