Breakthrough Made in Binge Eating Disorder

A study conducted by researchers at Boston University School of Medicine may provide clues for developing new treatments for compulsive binge eating. Compulsive binge eating is characterized by episodes of consuming more food than needed, often at a rapid pace. Binge eaters may also experience feelings of guilt, preoccupation with body weight, and mood swings. Compulsive binge eating affects an estimated 15 million people in the United States who are obese or have eating disorders. The study tested the potentially beneficial effects of activating a class of receptors in rats. Scientists identified Trace Armine-Associated Receptor, or TAAR1, as the key to treating binge eating. Researchers measured addiction-like behaviors in rats using sugary, chocolate-flavored food. Study co-author Adam Howell compared TAAR1 to a "brake" in the areas of the brain associated with decision-making. He said, "Subjects exposed to junk food lose this 'brake' and show aberrant addiction-like behavior over food. We are able to restore the function by activating this receptor." The study was published in the journal Neuropsychopharmacology,