Vesicles secreted from human heart cells may repair damaged tissue and prevent lethal heart rhythm disorders, according to a new study from investigators in the Smidt Heart Institute at Cedars-Sinai.
The research, published in the European Heart Journal, could lead to a new way to treat a heart rhythm problem called ventricular arrhythmia, a top cause of sudden cardiac death.
In an accompanying editorial, experts describe the research as "poised to turn this entire field on its head. "Ventricular arrhythmias can occur after a heart attack damaged tissue, causing chaotic electrical patterns in the heart's lower chambers. The heart ends up beating so rapidly that it cannot support the circulation, leading to a lack of blood flow and, if untreated, death.
The research, published in the European Heart Journal, could lead to a new way to treat a heart rhythm problem called ventricular arrhythmia, a top cause of sudden cardiac death.
In an accompanying editorial, experts describe the research as "poised to turn this entire field on its head. "Ventricular arrhythmias can occur after a heart attack damaged tissue, causing chaotic electrical patterns in the heart's lower chambers. The heart ends up beating so rapidly that it cannot support the circulation, leading to a lack of blood flow and, if untreated, death.
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