Charles V meets his bride Isabella of Portugal (Carlos, rey emperador)

Isabella of Portugal arrives to Spain and meets Francisco de Borja (Carlos, rey emperador)

Isabella of Portugal sends a letter to Charles V with Germaine of Foix (Carlos, rey emperador)

Charles V decides to marry Isabella of Portugal (Carlos, rey emperador)

The Imperial Wedding - Charles V and Isabella of Portugal (Carlos, rey emperador)

Isabella of Portugal learns that Charles V is engaged to another (Carlos, rey emperador)

Charles V leaves Spain and Empress Isabella as regent (Carlos, rey emperador)

Charles V decides to make Empress Isabella regent (Carlos, rey emperador)

Charles V and Empress Isabella reconciliation (Carlos, rey emperador)

King Charles refuses to marry Isabella (Carlos, rey emperador)

Charles V and Empress Isabella reconcile (Carlos, rey emperador)

Empress Isabella helps Charles V in ruling (Carlos, rey emperador)

King Charles meets his brother Ferdinand for the first time (Carlos, rey emperador)

Charles V meets Henry VIII and Katherine of Aragon (Carlos, rey emperador)

King Charles meets his mother Joanna the Mad after 11 years (Carlos, rey emperador)

Charles V frees his sister Catherine and makes her Queen of Portugal (Carlos, rey emperador)

King Charles sends his sister Eleanor to Portugal to marry the king (Carlos, rey emperador)

Empress Isabella is pregnant (Carlos, rey emperador)

Empress Isabella is Regent of Spain (Carlos, rey emperador)

Francisco de Borja confesses his feelings to Empress Isabella (Carlos, rey emperador)

Empress Isabella learns she is pregnant again (Carlos, rey emperador)