Isabella of Portugal arrives to Spain and meets Francisco de Borja (Carlos, rey emperador)

Francisco de Borja confesses his feelings to Empress Isabella (Carlos, rey emperador)

Charles V meets his bride Isabella of Portugal (Carlos, rey emperador)

Hernán Cortés arrives to Yucatán (Carlos, rey emperador)

Ferdinand of Austria arrives to the Court of Flanders (Carlos, rey emperador)

Charles of Habsburg arrives to Spain to become king (Carlos, rey emperador)

Charles V and Empress Isabella reconciliation (Carlos, rey emperador)

Empress Isabella learns she mustn't be pregnant again (Carlos, rey emperador)

Charles V and Empress Isabella reconcile (Carlos, rey emperador)

Empress Isabella helps Charles V in ruling (Carlos, rey emperador)

Empress Isabella is pregnant (Carlos, rey emperador)

Empress Isabella is Regent of Spain (Carlos, rey emperador)

Isabella of Portugal sends a letter to Charles V with Germaine of Foix (Carlos, rey emperador)

Charles V decides to marry Isabella of Portugal (Carlos, rey emperador)

The Imperial Wedding - Charles V and Isabella of Portugal (Carlos, rey emperador)

Charles V leaves Spain and Empress Isabella as regent (Carlos, rey emperador)

Empress Isabella learns she is pregnant again (Carlos, rey emperador)

Charles V decides to make Empress Isabella regent (Carlos, rey emperador)

King Charles refuses to marry Isabella (Carlos, rey emperador)

Empress Isabella helps Friar Bartolomé defend the Indians (Carlos, rey emperador)

Isabella of Portugal learns that Charles V is engaged to another (Carlos, rey emperador)