The lab-grown hearts, called organoids, are made from human stem cells, and destroyed after 28 days.
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00:00 [Music]
00:26 The way we measure damage is by looking at what the heart actually releases.
00:32 So, effectively, if a patient goes to a hospital to complain of a chest pain,
00:39 the things that a clinician would do is basically do an ECG followed by a blood test.
00:45 So, in vitro setting, on the bench, we try to mimic that.
00:50 [Music]
01:00 One of the hardest things with the heart is its low regenerative capacity.
01:04 So, the heart has a turnover of heart cells at a very low rate of 1%,
01:11 and by the time we reach 80 years of age, that significantly decreases by almost half.
01:17 So, if we can identify ways of trying to reverse those detrimental
01:22 or remove those detrimental cardiac heart cells, those cardiomyocytes,
01:26 we're hopefully able to keep the heart functioning as we want it to.
01:30 [Music]
01:35 Our next hope is to take that now more to the bedside and looking at the clinical side of this.
01:41 So, using ultrasounds or MRI imaging to integrate the AI into those sort of images,
01:49 and almost mimic what we've done here, but then using clinical images.
01:55 And so, it certainly has a lot of hope and promise to be used in the future.
02:01 [Music]