Painkiller Meftal Spas Can Cause ‘Adverse Reaction’, Indian government issues alert

2 years ago

Next time you pop a Meftal, a commonly used non-steroidal anti-inflammatory drug (NSAID), to get rid of your pain, do so after consulting a doctor on dosage and clarifying whether you need it at all. The Indian Pharmacopoeia Commission (IPC) has issued a drug safety alert about the common painkiller, saying its constituent, mefenamic acid, triggers severe allergic reactions like the DRESS syndrome, which affects your internal organs.

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Transcript

00:00 Next time you pop a meftal, a commonly used non-steroidal anti-inflammatory drug, to get

00:07 rid of your pain, do so after consulting a doctor on dosage and clarifying whether you

00:13 need it at all.

00:14 The Indian Pharmacopeia Commission has issued a drug safety alert about the common painkiller

00:19 saying its constituent, methanamic acid, triggers severe allergic reactions like the DRESS syndrome,

00:26 which affects your internal organs.

00:28 The methanamic acid painkiller is prescribed for the treatment of rheumatoid arthritis,

00:33 osteoarthritis, dysmenorrhea, mild to moderate pain, inflammation, fever, dental pain, period

00:38 pain, etc.

00:39 The commission in its alert said that a preliminary analysis of adverse drug reactions from the

00:45 Pharmacovigilance Programme of India database revealed DRESS syndrome.

00:50 DRESS syndrome is a severe allergic reaction caused by certain medicines.

00:55 Its symptoms include skin rash, fever, and lymphadenopathy, which can occur between two

00:59 and eight weeks after taking the drug.

01:01 "Health care professionals, patients and consumers are advised to closely monitor the possibility

01:05 of the above adverse drug reactions associated with the use of the above suspected drug,"

01:10 the alert said.

01:11 But doctors say the side effects are extremely rare, already known, and that they take care

01:15 to assess a patient while prescribing a limited dosage.

01:19 Many doctors confirmed that they hadn't seen adverse reactions during the practice, but

01:23 cautioned that reactions to the drug depended on the individual patient.

01:27 The real problem is unregulated overuse of the drug.

01:30 DRESS syndrome, i.e. drug rash with acinophilia and systemic symptoms, is a severe allergic

01:36 reaction affecting around 10% of individuals, potentially deadly and caused by certain medications.

01:42 It is characterized by fever, skin rash, lymphadenopathy, hematological abnormalities, and internal organ

01:48 involvement and manifests two to eight weeks after the drug has been taken.

01:52 Vigilance in medication usage is crucial to prevent this severe reaction.

01:56 Take the drug as per the advice of a medical professional only.

01:59 Furthermore, the IPC in their alert has said, in case of an adverse reaction, people should

02:03 immediately report to the National Coordination Centre of the PVPI by filing a form on their

02:08 website or through their helpline number 1800 180 3024.

02:12 [Music]

Painkiller Meftal Spas Can Cause ‘Adverse Reaction’, Indian government issues alert | Oneindia

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