Sensory inputs and motor output in the lamprey optic tectum in the intact brain using COLM

The visual input through the optic tract (OpT) to the optic tectum (OT), and the electrosensory afferents from the octavolateral area (OLA) are shown after a neurobiotin injection in the OT, in a cleared brain using the method CLARITY. The motor output can be also followed from the deep layer to the reticulospinal cells in the brainstem. The brain is shown from a dorsal view and in the bottom-left corner a schematic in a sagittal view can be seen. A moving bar indicates the approximate region shown at each moment. Areas of interest are annotated through the duration of the movie.

DOI: http://dx.doi.org/10.7554/eLife.16472.003